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One study

That is all it takes. A world of lies and myths have been developed because of one study. Cholesterol, depression, and diabetes are just a few cases of where isolated studies have led to massive changes in protocol. Sometimes the most influential studies are ones based on merely a single case, or a paper survey.

The worse thing to occur is when there are multiple studies that are used as a collection to arrive to a point, but that information was cherry picked or skewed to come to that conclusion. We see this a lot in research about carbohydrates and obesity for example.

A common place I am seeing this a lot right now is Xenoestrogens.

What is with that long X name?

Xenoestrogens (Zen-O-Estrogens) are a chemical compound made from man that in animals and humans mimic the effects of estrogen in the body. It is a by-product of various chemicals used in everyday things from drugs that we take to cosmetics and pesticides. There isn’t a specific Xenoestrogen, there are many kinds developed from many different sources.

The question of whether or not they are out there or if they can hurt you isn’t an issue. They are very much out there, and they can hurt you. The real question is what amount is going to cause you harm, how much does it take, and are you at risk? It would seem like a simple question to answer, one I actually think is, but in general these kinds of questions are never answered simply.

You were off by an aspirin

How much aspirin can you take before you would die from an overdose? Would taking one aspirin a day, everyday, for the rest of your life, do any good or harm?

When I ask you this question about aspirin you likely think of it in simple terms. You may not know how many at one time would kill you, but you would assume it would have to be a pretty extreme amount. As to how much you could take everyday, you may have a guess and you may have heard research, but you likely have a “one pill a day will likely not hurt most people” attitude.

How much alcohol would you have to drink before you would die from an overdose? Would having one drink of alcohol everyday, for the rest of your life, do any good or harm?

Alcohol is a poison to the body. Justify the few positive effects of a bottle of wine all you want, it is still a bottle of poison to the body. So why then do we have people throw out their bottles of water, and running in fear from steamed microwave vegetable bags, when these same people never question taking an aspirin or having a glass of wine?

Fear of the unknown

We know (pretty much) what aspirin is going to do to you. We know (pretty much) what alcohol is going to do to you. Now that we know, we simply have to roll the dice and take the chance.

Xenoestrogens however, we don’t know what it is going to do to us. Or do we? Do we actually have enough data and information to say for a fact now? That a little won’t hurt, but a lot will like everything else in the world? I propose that we do, but you can be the judge.

Logic gets in the way again

pest

The pesticide is the true starting point for this issue. Let’s skip through the technical and focus on a really simple to understand fact. A pesticide exists to kill a living thing.

Do you understand that concept, because I don’t think most of you do. Let’s not confuse a repellent with a pesticide either. A repellent does just that, it tries to stop or deter whatever it is from approaching. For example, the face I make at clubs when I almost get trapped in the two guy hump (not sexy by the way boys) is a replant.

If a date jumped in and beat them to death because they were trying to protect me, that would be a homicide. When you kill bugs, it is pesticide. They don’t get the chalk outlines and missing posters either.

If you took and continuing exposed yourself in large amounts to something that was made to kill something small, don’t you think that it is going to fuck you up? Yep. No brainer right? It is a poison made to kill something tiny. It is BS to say that it couldn’t hurt you if taken in large quantities. Xenoestrogens are just one of a many things in pesticides that could hurt you in you ingested large amounts of them.

The key note is the word large. Large is an undefined term and varies amongst different chemicals. If you type into Pubmed different chemicals and different toxicity levels, well, basically welcome to writing a 10 year novel. Even then you will likely miss something.

What are the definitive conclusions that we can draw? What do the studies say?

Over and over the studies show the following…

Events happen, such as the Alligators of Lake Apopka, the Roaches of the UK Sewage, and the Girls of Guatemala. These events all have a solid ties to Xenoestrogens and other chemicals, but there is one huge factor in all three of them. All three were in areas of high contamination of chemicals and pollution or even massive chemical spills.

Other things are high factors like patients on dialysis (blood bag contamination) etc. The amount absorbed is what is important, and even then so is the type.

The take home point is that in extreme contaminated situations are the only times that we are finding something going down. In small situations, even of continuous repeated contamination, we aren’t seeing anything weird.

This is likely due to the fact that our body is made to process and remove these things on small levels. If the level of intake of a poison is small enough, and non-aggressive enough, then usually we will filter it out okay. It is when it becomes too much to filter anymore that the problem comes in.

One could argue that overtime these things could breakdown that very defense. I don’t think this is an off base argument, however you have to look at the big picture, and don’t cheat the research we do have. If this is a concern for you then the best thing to do is to limit your contact with poisons. To that I will say good luck if stepping out side your front door or breathing in general if leaving in a populated area.

What about my damn water bottle!?

There are 3 main sources for your water bottle troubles.

Source 1-A grad student, a kid from the Idaho, did his thesis on water bottles and their repeated use and if it was safe. No peer review, we don’t even know what this kid did. He could have left them in a 102 degree temp car all day with backwash and god knows what.

He turns in his thesis stating that in fact he found higher levels of DEHA. DEHA was once listed toxic, but found later to “cannot be reasonably anticipated to cause irreversible chronic health effects” as stated by the Environmental Protection Agency. That isn’t what his thesis read, it stated that it was.

His “study” got shot out along the waves of press release and it found a winner with a major news organization. Next thing you know emails left and right go out about how your water bottle is going to hurt you. I assure you the spit you left in it from not cleaning it out is ten times more deadly.

Source 2-A study that is often confused with water bottles or plastic containers is actually a study done on cans, not bottles. In this study they found varying levels of BPA (Bisphenol A) in the cans. The food cans ranged from ravioli, soda, and infant formula. Some had higher levels than others and over all was stated as below the provisional tolerable daily intake of 25 μg/kg of body weight/day established by Health Canada.

Source 3-It has been shown that BPA can be leaked from boiling liquid in certain types of plastic bottles (ex. Nalgene). My first question is why the hell are you boiling water in a plastic bottle in the first place? Last time I looked the pots and pans you by at a store to boil water in, not made out of that material. I don’t know, maybe it is just me, but is seems that if something is made for something and you do it anyway, you are asking for trouble.

One woman asked me about boiling baby bottles. That is a question with legitimacy, and they have tested this and it wasn’t found to an issue.

To add to this it turns out that the myth of old bottles versus new bottles has been debunked as well. In fact, it appears that over time you are actually destroying the BPA with repeated boils. So the way to actually make BPA not an issue is to give it repeated boils over and over again as the levels decrease overtime.

The last question is, are the levels dangerous in the first place, and it would seem that dose levels found are within the guidelines of some countries standard, for instance the EFSA. Nothing we are seeing is reaching any sort of high level.

Wait, what about microwaved bowls!?

That doesn’t involve Xenoestrogens at all because it is a different type of plastic. A study was done to test the release of sexual hormones from various plastics and microwave bowls (saran wraps, etc) and the result?

The results thus indicate that neither the stabilizers and plasticizers used in PVDC films, nor their extracts, exert sex-hormonal activity.

It did release levels of ATBC and DOA, but these levels were not found to be toxic. So unless you start melting things and nuking them for abnormal (against directions) I think you are going to be okay.

Closing the lid

86067086

Here is where I take a moment and I put away the sane logic and the facts that we have to work with.

It is not without a doubt in my mind that we as a world are putting more out into this environment than it can take. What we put in our air, what we dump in to our water, what we spray on our fields, and what we do to our bodies in general is going to slowly destroy our world and bodies with it.

It is a lot easier to cry over a plastic bottle than to stop supporting the massive amount of energy companies, cars, factors, and chemical companies that make your life more convent.

Take home point, the water bottle isn’t likely to hurt you. The air you breath outside is. Think about that the next time you freak out over eating steam bag veggies. Do something useful and support the change for your daily waste, not crucifixion based on spotty research and MSN news leaks.


References

Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances.

Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida.

http://www.ncbi.nlm.nih.gov/pubmed/11351715?ordinalpos=10&tool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_

DefaultReportPanel.Pubmed_RVDocSum

Sexual disruption in a second species of wild cyprinid fish (the gudgeon, Gobio gobio) in United Kingdom freshwaters.

Migration of bisphenol A from polycarbonate baby bottles under real use conditions.

Bisphenol A (BPA) and its source in foods in Japanese markets.

Le, H. H., Carlson, E. M., Chua, J. P., and Belcher, S. M. 2008. Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons.

Maragou, N. C., Makri, A, Lampi, E. N., Thomaidis, N. S., and Koupparis, M. A. 2008. Migration of bisphenol A from polycarbonate baby bottles under real use conditions. Food Additives and Contaminants.

A summary report and full report are available on the EFSA website

Willhite, C. C., Ball, G. L., and McLellan, C. J. 2008. Derivation of a bisphenol A oral reference dose (RfD) and drinking-water equivalent concentration


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